Panton–Valentine leukocidin antibodies for the treatment of MRSA skin infections?

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منابع مشابه

An Outbreak of Severe Infections with Community-Acquired MRSA Carrying the Panton-Valentine Leukocidin Following Vaccination

BACKGROUND Infections with community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) are emerging worldwide. We investigated an outbreak of severe CA-MRSA infections in children following out-patient vaccination. METHODS AND FINDINGS We carried out a field investigation after adverse events following immunization (AEFI) were reported. We reviewed the clinical data from all case...

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Panton-Valentine Leukocidin and Staphyloccoccal Skin Infections in Schoolchildren1

The Panton-Valentine leukocidin is associated with staphylococcal skin and pulmonary infections. We describe a school outbreak of skin infections and the public health response to it. Nasal carriage of a Panton-Valentine leukocidin-positive Staphylococcus aureus clone was detected only in previously ill classmates and their family members.

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Panton-Valentine Leukocidin–Positive MRSA, Shanghai

fections. Prevalence of MRSA and distribution of MRSA sequence types in livestock in Italy are not known. However, surveys of foods of animal (pig) origin have showed an MRSA prevalence of 3.7% (1,10). In view of the low prevalence of MRSA ST398 in patients with no exposure to animals, food products currently seem to play a negligible role. However, this clone is likely spreading because of the...

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Trimethoprim-sulfamethoxazole or clindamycin for community-associated MRSA (CA-MRSA) skin infections.

BACKGROUND In the United States, community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has emerged as the predominant cause of skin infections. Trimethoprim-sulfamethoxazole (TMP-SMX) and clindamycin are often used as first-line treatment options, but clinical data are lacking. METHODS We conducted a retrospective cohort study of outpatients with skin and soft tissue infe...

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Increased Community-Associated Infections Caused by Panton-Valentine Leukocidin–Negative MRSA, Shanghai, 2005–2014

During 2005-2014, community-associated methicillin-resistant Staphylococcus aureus infections increased in Shanghai, China. Most infections were caused by sequence type 59 S. aureus that lacked Panton-Valentine leukocidin. This finding challenges the notion that Panton-Valentine leukocidin is necessary for epidemiologic success of community-associated methicillin-resistant S. aureus.

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ژورنال

عنوان ژورنال: Expert Review of Anti-infective Therapy

سال: 2011

ISSN: 1478-7210,1744-8336

DOI: 10.1586/eri.11.19